Faculty Member Receives NIH Award to Study Immune Biomarkers for Predicting Oral Cancer

Dr. Xiaoyuan Han is the first researcher at 91成人导航 to receive the SuRE-First award from the National Institutes of Health. Her research, in collaboration with Stanford School of Medicine, will use state-of-the-art single-cell analysis and bioinformatic artificial intelligence tools.

Dr. Xiaoyuan Han is the first researcher at 91成人导航 to receive the SuRE-First award from the National Institutes of Health. Her research, in collaboration with Stanford School of Medicine, will use state-of-the-art single-cell analysis and bioinformatic artificial intelligence tools.

Dr. Xiaoyuan Han, assistant professor in the Department of Biomedical Sciences at 91成人导航, Arthur A. Dugoni School of Dentistry, was recently awarded a Support for Research Excellence-First Independent Research (SuRE-First) Award from the National Institutes of Health (NIH) on the topic 鈥淪ingle-cell immune landscape in the oral dysplasia's malignant transformation.鈥

Dr. Han is the first researcher at 91成人导航 to receive the SuRE-First award, which aims to provide students, especially those from underrepresented groups, with research opportunities and enrich the research environment at institutions having limited NIH research support.

The award grants Dr. Han $702,000 for a four-year research project to identify immune features that predict the malignant transformation of cells in the mouth to oral cavity squamous cell carcinoma (OCSCC) using state-of-the-art single-cell analysis and bioinformatic AI tools.

鈥淥ur students will develop multiplex immune imaging assay on clinical dental biopsies and apply innovative bioinformatic AI tools on data analysis in my research project, which is a collaboration with Stanford School of Medicine,鈥 said Dr. Han. 聽

鈥淥CSCC is an aggressive cancer with a poor prognosis, and Dr. Han鈥檚 work could help to identify patients needing early care and increase our ability to provide personalized medical care to treat these patients,鈥 said Dr. David Ojcius, assistant dean for research and co-chair of the Department of Biomedical Sciences.

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